DIAGNOSIS: Schizophrenia

TREATMENT: Group Cognitive Remediation Therapy for Schizophrenia


  • Basic premise: "Cognitive functions such as executive function, learning & memory, processing speed, and sustained attention are frequently impaired and play an important role in the functional impairments seen in schizophrenia."
  • Essence of therapy: "Cognitive remediation (CR) or cognitive rehabilitation interventions are designed to improve cognitive function through repeated practice of cognitive tasks and / or strategy training. CR interventions are typically time-limited. They can be conducted individually or in groups. Some involve extensive use of computers while others focus primarily on paper-and-pencil tasks. Most CR interventions take into account the motivational and emotional deficits that are often present in schizophrenia as well. The goal of CR is to improve cognitive function. Research has shown small to medium effects of CR on neuropsychological measures of cognition, but whether these improvements are sustained or whether they translate into improved functioning remains unclear."



Compensatory Cognitive Training (CogSMART)

Integriertes Psychologisches Therapieprogramm bei schizophren Erkrankten IPT (Roder, V., Brenner, H. D., & Kienzle, N.)

INT-Integrated neurocognitive therapy for schizophrenia patients (Roder, V., Müller, D. R.)

Voices group protocol (Wykes, T. Hayward, P., & P, A. -M.)


CogSMART stands for: Cognitive Symptom Management and Rehabilitation Therapy (CogSMART)


Burlingame, G. M., Svien, H, Hoppe, L., Hunt, I., & Rosendahl, J. (2020). Group therapy for schizophrenia: A meta-analysis. Psychotherapy, 57(2), 219-236.

Farreny, A., Aguado, J., Ochoa, S., Huerta-Ramos, E., Marsà, F., López-Carrilero, R., Carral, V., Haro, J. M., & Usall, J. (2012). REPYFLEC cognitive remediation group training in schizophrenia: Looking for an integrative approach. Schizophrenia Research, 142(1-3), 137-144.

Katsumi, A., Hoshino, H., Fujimoto, S., Yabe, H., Ikebuchi, E., Nakagome, K., & Niwa, S. -I. (2019). Effects of cognitive remediation on cognitive and social functions in individual with schizophrenia. Neuropsychological Rehabilitation, 29(9), 1475-1487.

Keefe, R. S. E., Vinogradov, S., Medalia, A., Buckley, P. F., Caroff, S. N., D’Souza, D. C., Harvey, P. D., Graham, K. A., Hamer, R. M., Marder, S. M., Miller, D. D., Olson, S. J., Patel, J. K., Velligan, D., Walker, T. M., Haim, A. J., & Stroup, T. S. (2012). Feasibility and pilot efficacy results from the multisite cognitive remediation in the schizophrenia trials network (CRSTN) randomized controlled trial. The Journal of Clinical Psychiatry, 73(7), 1016-1022.

Kidd, S. A. Kaur, J., Virdee, G., George, T. P., McKenzie, K., & Herman, Y. (2014). Cognitive remediation for individuals with psychosis in a supported education setting: A randomized controlled trial. Schizophrenia Research, 157(1-3), 90-98.

Lecardeur, L., Stip, E., Giguere, M., Blouin, G., Rodriguez, J. -P., & Champagne-Lavau, M. (2009). Effects of cognitive remediation therapies on psychotic symptoms and cognitive complaints in patients with schizophrenia and related disorders: A randomized study. Schizophrenia Research, 111(1-3), 153-158.

Matsuda, Y., Morimoto, T., Furukawa, S., Sato, S., Hatsuse, N., Iwata, K., Kimura, M., Kishimoto, T., & Ikebuchi, Em. (2018). Feasibility and effectiveness of a cognitive remediation programme with original computerised cognitive training and group intervention for schizophrenia: a multicentre randomised trial. Neuropsychological Rehabilitation, 28(3), 387-397.

Mendella, P. D., Burton, C. Z., Tasca, G. A., Roy, P., St. Louis, L., & Twamley, E. W. (2015). Compensatory cognitive training for people with first-episode schizophrenia: Results from a pilot randomized controlled trial. Schizophrenia Research, 162(1-3), 108-111.

Morimoto, T., Matsuda, Y., Matsuoka, K., Yasuno, F., Ikebuchi, E., Kameda, H., Taoka, T., Miyasaka, T., Kichikawa, K., & Kishimoto, T. (2018). Computer-assisted cognitive remediation therapy increases hippocampal volume in patients with schizophrenia: a randomized controlled trial. BMC Psychiatry, 18(83).

Mueller, D. R., Schmidt, S. J., & Roder, V. (2015). One-year randomized controlled trial and follow-up of integrated neurocognitive therapy for schizophrenia outpatients. Schizophrenia Bulletin, 41(3), 604-616.

Mueller, D. R., Khalesi, Z., Benzing, V., Castiglione, C. I., & Roder, V. (2017). Does Integrated Neurocognitive Therapy (INT) reduce severe negative symptoms in schizophrenia outpatients? Schizophrenia Research, 188, 92-97.

Rakitzi, S., Georgila, P., Efthimiou, K., & Mueller, D. R. (2016). Efficacy and feasibility of the Integrated Psychological Therapy for outpatients with schizophrenia in Greece: Final results of a RCT. Psychiatry Research, 242, 137-143.

Sánchez, P., Peña, J., Bengoetxea, E., Ojeda, N., Elizagárate, E., Ezcurra, J., & Gutiêrrez, M. (2014). Improvement in negative symptoms and functional outcome after a new generation cognitive remediation program: A randomized controlled trial. Schizophrenia Bulletin, 40(3), 707-715.

Tan, S., Zou, Y., Wykes, T., Reeder, C., Zhu, X., Yang, F., Zhao, Y., Tan, Y., Fan, F., & Zhou, D. (2016). Group cognitive remediation therapy for chronic schizophrenia: A randomized controlled trial. Neuroscience Letters, 626, 106-111.

Twamley, E. W., Vella, L., Burton, C. Z., Heaton, R. K., &  Jeste, D. V. (2012). Compensatory cognitive training for psychosis: Effects in a randomized controlled trial. The Journal of Clinical Psychiatry, 73(9), 1212-1219.

Vauth, R., Corrigan, P. W., Clauss, M., Dietl, M., Dreher-Rudolph, M., Stieglitz, R. -D., & Vater, R. (2005). Cognitive strategies versus self-management skills as adjunct to vocational rehabilitation. Schizophrenia Bulletin, 31(1), 55-66,

Wölwer, W., Frommann, N., Halfmann, S., Piaszek, A., Streit, M., & Gaebel, W. Remediation of impairments in facial affect recognition in schizophrenia: Efficacy and specificity of a new training program. Schizophrenia Research, 80(2-3), 295-303.